We already know that the Sharingan see chakra flow within an person as well as see chakra in general. For those who have read the Sasuke vs Deidara fight, we have witnessed Sasuke utilizing his Sharingan to see chakra EVEN THROUGH THE GROUND!
http://www.onemanga.com/Naruto/361/17/I'm guessing the mines were like 3 inches deep underground. Through that evidence alone, I would say that the Sharingan can see chakra through smoke, hence seeing someone (to be more specific, the person's chakra flow) within the smoke itself.
However, there's another side of me that wants to deny that possibility for a few reasons...
1. It will get all those Sharingan fanboys all excited -.-
2. In a sense it's another trait that cancels out the Byakugan. I mean Byakugan main ability is sight in terms of range and focus. I mean I'm sure the Byakugan can see through smoke but knowing that the Sharingan can as well (in terms of locating a person), doesnt make Byakugan all that special. However the difference between them are still range.
I cant say there is that much of a difference in focus since Sasuke was able to see Deidara's microscopic bombs:
http://www.onemanga.com/Naruto/361/03/ 3. I dont know, it just feels like an act of god-modding to do if use it in the zones.
Which actually leads to another discussion of is it really impossible for the Sharingan to see chakra points? I mean most of our information about Sharingan in terms of detail was from Kakashi's Sharingan and during Part 1 of Naruto, he didnt completely master his Sharingan.
http://www.onemanga.com/Naruto/79/17/He states HIS sharingan cant see these chakra points, which are the size of a needle tip, yet Sasuke is able to see a microscopic jutsu. >.>
But anyways, back on topic with the smoke bombs, give me thoughts on it.