Uhh, so everyone suddenly forgot Kaguya's the origin of kaguya clan, and first user of shikotsumyaku ever too? They even have the same lame face dots.
To repeat myself, I wasn't talking KGs, but genetics-wise. The closest you can get to being ootsutsuki on SL is either being uchiha + senju, or hyuga + kaguya.
Actually, Kaguya herself was
of the Otsutsuki clan. Their leader too, until her sealing. From there, Hamura becomes their leader and migrates with them to the moon. Hagoromo stays on earth to do his thing. Interesting thing about the clan though. They're born by default with Byakugan, like the Hyuuga. The reason why they have doujutsu in the first place, is because they're from "another world" as stated in the fourth databook. This is also Toneri's motivation behind destroying the world and taking Hinata: to recreate it and "make" another Kaguya with her. (It's also because she's of the Hyuuga, and had apparently inherited a stronger portion of Hamura's chakra.)
Picture very related.
The Rinnegan/Sharingan didn't become a thing until Kaguya ate the chakra fruit. So really, all clans with KG are from the Otsutsuki, or Kaguya to be more specific. But it's become more apparent that the two original holders of the Six Paths Chakra, Hagoromo and Hamura, are what make the the clans that are the most-closely associated with being their descendants (Uchiha, Senju, Hyuuga and Otsutsuki) the most powerful.
But yes, apparently the Hyuuga were either a sect of the Otsusuki that were left on earth, or were propagated from Hamura having some kinda thing with some earth chick. If it were the latter, he definitely chose very well.